Last edited by Dashakar
Thursday, August 13, 2020 | History

5 edition of Percutaneous Absorption found in the catalog.

Percutaneous Absorption

Mechanisms-Methodology-Drug Delivery (Dermatology)

by Robert L. Bronaugh

  • 110 Want to read
  • 32 Currently reading

Published by Marcel Dekker Inc .
Written in English

    Subjects:
  • Skin Absorption,
  • Dermatology,
  • Pharmacodynamics,
  • Science/Mathematics,
  • Transdermal medication,
  • Permeability,
  • Skin

  • Edition Notes

    ContributionsHoward I. Maibach (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages664
    ID Numbers
    Open LibraryOL8126232M
    ISBN 100824780361
    ISBN 109780824780364

    More generally, "percutaneous", via its Latin roots means, 'by way of the skin'. An example would be percutaneous drug absorption from topical medications. More often, percutaneous is typically used in reference to placement of medical devices using a needle stick approach.   Percutaneous Absorption is a new addition to the literature, which reviews the permeability of skin and complements the other recent volumes by Barry (Dermatological Formulations: Percutaneous Absorption) and Schaefer et al (Skin Permeability).It will interest those who are concerned with transdermal drug delivery and toxicology. The book evolved Author: Steven Jacques.

    Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in motion by percutaneous absorption of UV filters in sunscreen cosmetic products. León describes these methods in both in vitro and non-invasive in vivo methodologies. Currently. This state-of-the-art book is an ideal instructional manual for investigators uninitiated in performing percutaneous absorption and metabolism studies. Those involved with investigative dermatology, dermatological research, toxicology, and pharmacology will find this reference interesting and indispensable.

    Define percutaneous absorption. percutaneous absorption synonyms, percutaneous absorption pronunciation, percutaneous absorption translation, English dictionary definition of percutaneous absorption. He was completely absorbed in his book.,, abˈsorbent adjective. able to soak up. absorbent paper., abˈsorption (-ˈzoːp-) noun; ; ab. Complete with nearly drawings, photographs, equations, and tables and more than bibliographic citations of pertinent literature, Percutaneous Absorption, Third Edition details the applied biology of percutaneous penetration factors that affect skin permeation, such as age, vehicles, metabolism, hydration of skin, and chemical.


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Percutaneous Absorption by Robert L. Bronaugh Download PDF EPUB FB2

About this Item: Marcel Dekker, New York, Hardcover. Condition: Very Good Ex-Library Cond Book. pgs. Covers the skin's role as a portal of entry for chemical into the body; explains the pathways of penetration, mathematical models, metabolism, in vitro and in vivo techniques for measuring absorption, various factors that influence methodology, procedures.

The detail is beyond anything found in an anotomy book, and is essential information for understanding percutaneous absorption. There is a chapter that details the pharmokinetics of skin absorption.

This is excellent reading for understanding Cited by: Get this from a library. Skin barrier: principles of percutaneous absorption. [H Schaefer; Thomas E Redelmeier] -- Skin Barrier is the first book to be written exclusively by researchers for researchers as a convenient desktop reference.

It focuses on several key aspects of the skin barrier including composition. Dermatological formulations: Percutaneous absorption. By Brian W. Barry. Marcel Dekker, Madison Avenue, New York, NY pp. 16 × cm. Price $ ( higher outside the US.

and Canada)Cited by: 3. The stratum corneum is that layer of the epidermis which functionally is the most important in limiting percutaneous absorption, showing the characteristics of a composite semipermeable membrane.

A mathematical expression of transepidermal diffusion may be derived from Fick's Law of mass transport; factors altering the rate of diffusion are. Updating and expanding the scope of topics covered in the previous edition, this Fourth Edition supplies new chapters on topics currently impacting the field including cutaneous metabolism, Percutaneous Absorption book contamination, exposure to protein allergens, in vitro absorption methodology, the percutaneous absorption of chemical mixtures, the penetration of chemicaBook Edition: 4th Percutaneous Absorption book.

Principles of Percutaneous Absorption * H. Schaef er, G. Stiittgen, W. Schalla, J. Gazith and E. Bauer Dermatology Clinic of the Free University of Berlin, Rudolf-Virchow-Hospital, West Berlin ABSTRACT Percutaneous absorption is a passive diffusion process.

T n e main obstacle is the horny layer (stratum corneum).Cited by: percutaneous absorption: the absorption of drugs, allergens, and other substances through unbroken skin. The corneal layer of epidermis is the. Percutaneous absorption: mechanisms--methodology--drug delivery.

Robert L. Bronaugh, Howard I. Maibach. Dekker, - Medical - pages. 0 Reviews. From inside the book. What people are saying - Write a review. We haven't found any reviews in the usual places.

Contents. Since publication of the Second Edition innumerous innovations have occurred that affect the way scientists look at issues in the field of percutaneous absorption. Focusing on recent advances as well as updating and expanding the scope of topics covered in the previous edition, Percutaneous Absorption, Third Edition provides thorough coverage of the skin's role as an 2/5(1).

Methods of in vitro percutaneous absorption are widely used to measure the absorption of topically applied compounds. A major advantage of in vitro systems is that they can be used to test compounds that are too toxic to test in humans.

Metabolism can be measured if viable skin is obtained and the viability is maintained in the diffusion cells. ISBN: OCLC Number: Description: XXI, p.: gràf. ; 24 cm: Contents: Mechanisms of absorption: mathematical models in percutaneous absorption; cutaneous metabolism during in vitro percutaneous absorption; cutaneous metabolism of Xenobiotics; occlusion does not uniformly enhance penetration in vivo; regional variationin.

The skin is an evolutionary masterpiece of living tissue which is the final control unit for determining the local and systemic availability of any drug which must pass into and through it. In vivo in humans, many factors will affect the absorption of drugs. These include individual biological variation and may be influenced by race.

The skin site of the body will also Cited by: Full Description:" Percutaneous absorption can improve the reader's memory. As you read the book, you have a variety of meanings, their origins, ambitions, history and nuances, as well as various circles and sub-transfers each story.

Just a little to remember, but the brain is a beautiful thing and relatively easy to remember these things. Abstract. Historically the topical application of therapeutic agents to the skin dates back to ancient Babylonian and Egyptian medicine.

The widespread scientific investigations leading to our current concepts of the physiology of percutaneous absorption, however, are of recent origin. Start studying Pharmacology Final. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Factors concerning drug absorption that are important in patient teaching are Factors concerned with percutaneous absorption include the *length of the time the medication is in contact with the skin *moisture level of the.

Book Author(s): Deutsche Forschungsgemeinschaft. Search for more papers by this author Normal working clothes do not generally provide any protection against percutaneous absorption. Quantification of the amount of a substance absorbed through the skin can only be realized by biological monitoring.

Substances are designated with an “H. Predictive Methods in Percutaneous Absorption. Authors: Moss, Gary, Gullick, Darren, Wilkinson, Simon Free Preview. Provides a comprehensive critique of models of percutaneous absorption, their source data and both their limitations and correct use The book will be of interest to all researchers in academia and industry working in.

Of the various approaches employed to enhance the percutaneous absorption of drugs, occlusion (defined as the complete impairment of passive transepidermal water loss at the application site) is the simplest and perhaps one of the most common methods in by: Dermatological Formulations: Percutaneous Absorption (Drugs and the Pharmaceutical Sciences) by Barry, Brian W.

and a great selection of related books, art and collectibles available now at. Read "Percutaneous Absorption of UV Filters Contained in Sunscreen Cosmetic Products Development of Analytical Methods" by Zacarías León González available from Rakuten Kobo.

Zacarías León's thesis describes the development and validation of analytical methods to estimate the processes set in m Brand: Springer International Publishing.Request PDF | Predictive Methods in Percutaneous Absorption | This book sheds new light on the development and use of quantitative models to .percutaneous absorption (6), but this process is not rate limiting in terms of actual absorbed dose, although it may affect the nature of the material entering the bloodstream.

l/8. OECD/OCDE. PRINCIPLE OF THE TEST 5. The test substance, which may be radiolabelled, is applied to the surface of a skin sample.